Publications

Select Publications
  • Gutierrez-Arcelus M, Teslovich N, Mola AR, Kim H, Hannes S, Slowikowski K, Watts GFM, Brenner M, Raychaudhuri S, Brennan PJ. Lymphocyte innateness is defined by underlying transcriptional states reflecting a balance between proliferation and effector functions. Nat Comm. 2019. Feb 8;10(1):687.
  • Lee-Sarwar K, Kelly RS, Lasky-Su J, Moody DB, Mola AR, Cheng TY, Comstock LE,  Zeiger RS, O’Connor GT, Sandel MT, Bacharier LB, Beigelman A, Laranjo N, Gold DR, Bunyavanich S, Savage JH, Weiss ST, Brennan PJ*, Litonjua AA. Intestinal microbial-derived sphingolipids are inversely associated with childhood food allergy. J Allergy Clin Immunol. 2018 May 2.
  • Brennan PJ, Cheng TY, Pellicci DG, Watts GFM, Veerapen N, Young DC, Rossjohn J, Besra GS, Godfrey DI, Brenner MB, Moody DB. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8348-8353.
  • Brennan PJ, Tatituri RV, Heiss C, Watts GFM, Hsu FF, Veerapen N, Cox LR, Azadi P, Besra GS, Brenner MB. Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction. Proc Natl Acad Sci USA. 2014 Sep 16;111(37):13433-8.
  • Cohen NR, Brennan PJ*, Shay T, Watts GF, Brigl M, Kang J, Brenner MB & The Immunological Genome Project Consortium. Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. Nat Immunol. 2013;14(1):90-9.
  • Brennan PJ, Tatituri RV, Brigl M, Kim EY, Tuli A, Sanderson JP, Gadola SD, Hsu FF, Besra GS, Brenner MB. Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals. Nat Immunol. 2011;12(12):1202-11.
Reviews
  • Brennan PJ, Brigl M, Brenner MB. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions [review]. Nat Rev Immunol. 2013;13(2):101-17.
  • Kim EY, Lynch L, Brennan PJ, Cohen NR, Brenner MB. The transcriptional programs of iNKT cells. [review] Semin Immunol. 2015 Feb;27(1):26-32.
  • Kohlgruber AC, Donado CA, LaMarche NM, Brenner MB, Brennan PJ. Activation strategies for invariant natural killer T cells. Immunogenetics. 2016 Aug;68(8):649-63.
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